The study of computing in medical applications has opened many challenging issues and problems for both the medical computing and mathematical communities. This workshop is intended to foster communication and collaboration between researchers in the medical computing community and researchers working in applied mathematics and optimization.

Mathematical techniques (continuous and discrete) are playing a key role with increasingly importance in understanding several fundamental problems in medicine.

For instance, mathematical theory of nonlinear dynamics and discrete optimization has been used to predict epileptic seizures.
Next to stroke, epilepsy is among the most common disorders of the nervous system. Measures derived from the theory of nonlinear dynamics and discrete optimization techniques are used for prediction of impending epileptic seizures from analysis of multielectrode electroencephalographic (EEG) data.

Several examples of the use of
mathematics in medicine can be found in recent cancer research.
Sophisticated mathematical models and algorithms have been used for generating treatment plans for radionuclide implant and external beam radiation therapy. With Gamma Knife treatment, for example, optimization techniques have been used to automate the treatment planning process.

Optimization has been used to
address a variety of medical image registration problems. In particular, specialized mathematical programming techniques have been used in a variety of domains including the rigid alignment of primate autoradiographs and the non-rigid registration of cortical anatomical structures as seen in MRI.

The invited presentations will be complemented by sessions of contributed talks.